Nana was designed to be the first voice on the Mac OS. She was inspired by the success of Hatsune Miku, and was even labelled Macne Miku (Mac音ミク) during her first production. She is described as a bright and cheerful girl who can be a bit of a klutz. She is accident prone and is often late for work, but always looks on the bright side of life. She and her sisters run the "Mac Sound (Macne) Cafe" (Mac音カフェ).
Her first design is mainly inspired by Hatsune Miku, while the 2S design has been said to be "princess" themed. The design of the Macne series in general incorporate various aspects of the Mac computer and its physical appearance, such as USB ports and disk drives or portable devices such as the i-pod.
Macne Nana was originally released in Open license format for Reason4 and GarageBand, and contained 104 samples. Due to the fact it was released as a open license, so long as you owned the original software Nana was free to be exploited to additional software. This led it to later be converted to work with UTAU by UTAU fans.
A smaller "compact" version called "Macne Nana Petite" was also released at a cheaper price, with less content and was released as the "lite" version of Macne Nana. When the Act2 website was retired and the Macne's were moved over to their own website, Macne Nana and Macne Nana Petite (now called "Macne Petite") were given new vocals called "Macne Nana 2S" and "Macne Petite 2S".
The "Macne Nana 2S" version was recorded in the scales of D#4/G#4/C#5 and had 117 samples, more than the first Macne Nana release. It came with a already built UTAU vocal and was made to sound more distinct from Macne Petite, as well as the original "Macne Nana/Macne Nana Petite" vocal.
Macne Nana was originally developed as the "sound Princess for the Mac" and had much marketing prior to being considered for VOCALOID™. This included merchandise for her such as a keyboard with her image printed on it and a G3 iPhone.
While she was not as popular for her intended software Garageband, Macne Nana was fairly popular with UTAU users. The vocal samples that made up the Macne series presented a "VOCALOID-like" quality to which was often absent from UTAU vocals.
The overall success for Macne Nana and Macne Nana Petite led to further Macnes being produced. The concept of the Macnes being a family unit proved popular with their fans and it was carried on with all further releases.